Edrophonium?hyoscine butylbromide mixture in neonates

pharmacotherapy Update: Hyoscine Butylbromide in the Treatment of Abdominal spasms

Abdominal pain is one of the most common reasons why people seek medical care, and is often due to spasm of intra-abdominal visceral organs. Hyoscine butylbromide (HBB) is a quaternary ammonium compound which blocks the action of acetylcholine at parasympathetic sites (both muscarinic and nicotinic receptors) in smooth muscle, and in secretory glands. It causes decreased motility of the gastroi...

Rabbit Neonates and Human Adults Perceive a Blending 6-Component Odor Mixture in a Comparable Manner

Young and adult mammals are constantly exposed to chemically complex stimuli. The olfactory system allows for a dual processing of relevant information from the environment either as single odorants in mixtures (elemental perception) or as mixtures of odorants as a whole (configural perception). However, it seems that human adults have certain limits in elemental perception of odor mixtures, as...

Studies on the development of rapidly disintegrating hyoscine butylbromide tablets.

The objective of this study was to prepare hyoscine butylbromide (a drug with bitter taste) tablets that can rapidly disintegrate in saliva. The granules were prepared by the extrusion method using aminoalkyl methacrylate copolymers (Eudragit E-100). The drugs dissolved rapidly in medium at pH 1.2 in a dissolution test while none of the drugs dissolved from the granules (% of dissolved < 5%) ev...

Angioneurotic oedema and urticaria induced by hyoscine butylbromide.

Case report A 23-year-old white female was admitted to hospital following the sudden onset of swelling of her eyelids, urticarial lesions on her trunk and extremities and a feeling of tightness in her throat. The patient was being treated symptomatically for abdominal colic with hyoscine butylbromide (Buscopan) 10 mg three times a day and had taken one week's supply before the onset of her symp...

Effect of hyoscine butylbromide on cervical dilation during labor